TransposeNet

Massachusetts Institute of Technology (mit)
Computer Science and Artificial Intelligence Laboratory (csail)
Theory of Computation Group (toc)
Berger Lab for Computation and Biology (compbio)

Corresponding author for study: fraenkel@mit.edu, bab@mit.edu, and lindquist_admin@wi.mit.edu
Queries regarding usage of TransposeNet pipeline: jianpeng@illinois.edu, bab@mit.edu, and vikram_khurana@me.com

Pipeline

TransposeNet Pipeline

Reference

The TransposeNet framework is explained in the following study:

Khurana V†, Peng J†, Chung CY†, Auluck PK, Tardiff DF, Fanning S, Bartels T, Koeva M, Eichhorn SW, Benyamini H, Lou Y, Nutter-Upham A, Baru V, Freyzon Y, Tuncbag N, Costanzo M, San Luis BJ, Schöndorf DC, Barrasa MI, Ehsani S, Sanjana N, Zhong Q, Gasser T, Bartel DP, Vidal M, Deleidi M, Boone C, Fraenkel E*, Berger B*, and Lindquist S*. Genome-scale networks link diverse molecular pathways and neurodegenerative disease genes to alpha-synuclein. (to appear in Cell Systems)

† = joint first authors
* = co-corresponding authors

Instructions

This section is under construction.

  1. Run DCA tool for human homologs
  2. Build SteinerNet ensemble.

Data

This section is under construction.